Jan 10, 2020 · We also evaluated results in four levels of D vitamin as a severe deficiency, deficiency, insufficiency, and sufficiency. Results: Architect showed 9.59% bias from LC-MS/MS with smaller mean. Passing-Bablok regression analysis demonstrated the value of 0.95 slope and had a constant bias with an intercept value of -4.25.
Apr 9, 2023 · A serum level of 25-hydroxyvitamin D (25 OH D) of at least 30 ng/ml (78 nmoL/L) is required to maintain the physiologic function of vitamin D. Recommendations are to use 25-hydroxyvitamin D (25 OH D) as a measure of vitamin D status as it has a half-life of 2 weeks; whereas, 1,25-dihydroxy vitamin D (1,25 (OH)), the biologically active form
Vitamins. Vitamin D. 25-hydroxyvitamin D. Vitamin D, either in its D2 or D3 form, is essential for normal human development during intrauterine life, kidney function and bone health. Vitamin D deficiency has also been linked to cancer development and some autoimmune diseases. Given this huge impact of vitamin D on huma ….
Consequently, accurate measurements of 1,25 (OH) D can aid in the differential diagnosis of calcium-related disorders such as hypocalcemia in vitamin D-dependent rickets and hypercalcemia due to inappropriate increase of serum 1,25 (OH) D in granulomatous diseases. However, due to its lipophilicity and very low circulating concentration, the
Nov 27, 2022 · Presently, we still cannot draw any definite conclusion for the association between vitamin D status and the mortality of AKI, due to limited published data. 1,25(OH)2D is formed mainly in the
Sep 25, 2020 · To assess the association between vitamin D sufficiency and severity of the disease, all patients were categorized based on cut point of 30 ng/mL for 25(OH)D as recommended by the Endocrine Society. 14 Our data revealed that a 25(OH)D levels of at least 30 ng/mL was associated with a significant decrease in the severity of clinical outcomes
Sep 5, 2013 · Serum 25(OH) vitamin D levels were significantly inversely associated with liver cancer incidence (Q4 vs Q1, OR=0.43, 95% CI=0.21–0.89) among those with baseline levels of serum calcium higher
Nov 15, 2017 · There is substantial evidence that the prevalence of vitamin D deficiency is unacceptably high in the population, and this requires action from a public health perspective. Circulating 25-hydroxyvitamin D [25(OH)D] is a robust and reliable marker of vitamin D status and has been used by numerous age …
May 14, 2011 · In addition, immunoassays for 25OHD have been reported to cross-react with 24,25(OH) 2 D3, an intermediate product during the formation of 1,25(OH) 2 D3 in the kidney [16, 17] (Figure 1). Many commercial immunoassays can only measure 25OHD3 and are not suitable to monitor supplementation with Vitamin D2, which is derived from plant sources and
May 18, 2016 · Controversy persists over: 1) how best to restore low serum 25-hydroxyvitamin D (25D) levels (vitamin D2 [D2] vs vitamin D3 [D3]); 2) how best to define vitamin D status (total [protein-bound + free] vs free 25D); and 3) how best to assess the bioactivity of free 25D.
• 100 IU/day raises serum concentration of 25(OH)D by 1 ng/mL • Serum 25(OH)D is safe up to 100 ng/mL and perhaps 200 or 300 ng/mL – Toxic levels are reported at 150 ng/mL • 10,000 IU/day Tolerable Upper Intake Level (no toxicity observed up to 5 months) • Increased risk of kidney stones with excess calcium intake (1000 mg)
Vitamin D deficiency is a worldwide pandemic. The aim of this study was to evaluate associations of plasma 25(OH)D levels with the likelihood of coronavirus disease 2019 (COVID-19) infection and hospitalization. The study population included the 14 000 members of Leumit Health Services, who were tes …
Jul 29, 2019 · 1. Introduction. Measurement of 25-Hydroxyvitamin D (25-OH-D) is commonly performed to assess Vitamin D status in clinical laboratories. Vitamin D can be synthesized in skin from 7-dehydrocholesterol following ultraviolet light exposure, which produces Vitamin D3 (cholecalciferol).
Jul 22, 2020 · This systematic review supported an association between serum vitamin D levels (measured in ng/mL of 25 (OH)D) and chronic periodontitis, with an overall SORT A recommendation. Within the lack of the available studies, salivary levels of 25 (OH)D did not present an association with chronic periodontitis. In addition, there was a scarcity of
Mar 1, 2022 · Mitochondrial vitamin D 25-hydroxylase converts vitamin D 3 to 25(OH)D 3 five times faster than it converts vitamin D 2 to 25(OH)D 2. In a systematic review and meta-analysis, Tripkovic et al 14 concluded that supplementation with vitamin D 3 had a significant and positive effect in the raising of serum 25(OH)D concentrations compared with the
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